FIGURE 5: Suppression by Cox1 I101F is restricted to cox23Δ cells.

(A) cox17Δ or cox19Δ was introduced to BY haploid wild-type nuclear DNA with or without Cox1 I101F mtDNA mutation and plated on YPD and YPGL plates for 3 and 7 days at 30°C respectively.

(B) coa1Δ, coa2Δ or shy1Δ was introduced to BY haploid wild-type nuclear DNA with Cox1 I101F mtDNA mutation and plated on YPD and YPGL plates and incubated at 30°C for 3 and 7 days respectively.

(C) cox23Δ cells were transformed with MSS51, SHY1, COA1 or COA2 overexpression plasmids and plated on YPD and YPGL plates and incubated for 3 and 7 days at 30°C respectively.

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