FIGURE 5: MPC1 inactivation increases glyoxylate/gluconeo-genesis and reduces respiration during chronological aging.

At the indicated time points Icl1 (A) and Pck1 (B) enzymatic activities of wt and mpc1Δ mutant cells were measured.

In parallel, cellular respiration (C) was also monitored.

Day 0, diauxic shift. Data refer to mean values determined in three independent experiments. SD is indicated. * P ≤ 0.05 and ** P ≤ 0.01.