Back to article: Transcriptomic and chemogenomic analyses unveil the essential role of Com2-regulon in response and tolerance of Saccharomyces cerevisiae to stress induced by sulfur dioxide

FIGURE 3. (A) Comparison of the susceptibility towards SO2 of the mutants devoid of the expression of genes whose transcription is activated in response to SO2 in a Com2p-dependent manner. Cells of the parental strain (wt) and of the indicated deletion mutants were grown until mid-exponential phase in liquid MMB medium (at pH 3.5) and then used to inoculate the same basal medium either supplemented (open symbols) or not supplemented with 0.5 mM SO2 (filled symbols) (at pH 3.5). Cells were batch cultured at 30ºC and growth was monitored based on OD620nm. The growth curves presented are representative of at least three independent growth experiments. (B) Wild-type strain was challenged for 24h in MMB pH 3.5 without and/or with 0.5 mM SO2 supplemented with 1 g/L of lysine.

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