Back to article: Genome-wide analysis of yeast expression data based on a priori generated co-regulation cliques

FIGURE 2: Analysis of microarray data sets on pheromone response. (A) Response to α-pheromone with data from [37]. Downregulation is shaded in four levels of green, upregulation in four levels of red. Genes, which are in the clustered network, but received no values in the experiment, were blanked out. Significantly changed cliques in replicate 1 are highlighted with yellow background and labelled with their clique name. (B) Comparison between two replicates in respect to average expression changes in the 72 cliques. We marked the cliques that are significantly changed in respect to average expression in both experiments (p<0.0001) in the plot with red (upregulation) and green (down-regulation) and labelled them accordingly. (C) UpRegScore for each cluster in the two replicates. Cliques, where both replicates showed significant shifts in the same direction were labelled in red (upregulation) or green (downregulation). We named them accordingly.

37. Tirosh I, Weinberger A, Bezalel D, Kaganovich M, Barkai N (2008). On the relation between promoter divergence and gene expression evolution. Mol Syst Biol 4: 159. doi: 10.1038/msb4100198

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