Back to article: Metabolic reprogramming of Salmonella infected macrophages and its modulation by iron availability and the mTOR pathway


image description

FIGURE 4: Infection but not iron perturbations induces mTOR activation in macrophages. Protein levels of the mTOR downstream target p4E-BP1 were determined using Western blot analysis after treating RAW264.7 cells with Salmonella (MOI of 10) for 1 h. Additionally, cells were treated with FeCl3/hepcidin (50 μM/1 μg/ml, respectively) or DFP (50 μM) for 6 h prior to infection.

By continuing to use the site, you agree to the use of cookies. more information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this. Please refer to our "privacy statement" and our "terms of use" for further information.

Close