Back to article: A novel antibacterial strategy: histone and antimicrobial peptide synergy


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FIGURE 1: Model of antibacterial synergy between mammalian histones and pore-forming antimicrobial peptides (AMPs). AMPs induce pore formation in bacterial membranes, which facilitates the entry of histones. Histones stabilize AMP-induced pores, reorganize the chromosome, and inhibit transcription.

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