Back to article: A new role for proteins subunits of RNase P: stabilization of the telomerase holoenzyme

image description

FIGURE 1. (a) Table presents names of proteins in RNase P and MRP in both S. cerevisiae and H. sapiens; (+) and (-) indicate presence or absence of the protein in the indicated RNase complex. Names of three Pop proteins that are telomerase-associated in S. cerevisiae are in red. (b) Structure of the 340 nt RNase MRP RNA subunit, NME, bound by Pop1 (red; ~100kDa), Pop6 (orange; ~18 kDa), Pop7 (tan; ~16 kDa) at the P3 stem-loop domain. (c) Diagram of the 1157 nt S. cerevisiae telomerase RNA, TLC1, bound by the core holoenzyme protein components. Expanded area depicts the Cs2a/TeSS (P3-like) domain in TLC1 to which Pop1, 6, and 7 bind. Images were made in BioRender (

By continuing to use the site, you agree to the use of cookies. more information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this. Please refer to our "privacy statement" and our "terms of use" for further information.