Back to article: Too much of a good thing: Overproduction of virulence factors impairs cryptococcal pathogenicity

FIGURE 1: The transcription factor Pdr802 is a negative regulator of cryptococcal capsule thickness and Titan cell formation. Upper panel, India ink staining of fungal cells isolated from the lungs of mice infected with the wild-type (KN99α), deleted (pdr802), and complemented (PDR802) strains at 3 days post-infection. Lower panel, India ink staining of the same strains after growth in Titan cell induction media in vitro for 72 hours at 37°C and 5% CO2. All images are to the same scale; scale bar, 10 µm.

By continuing to use the site, you agree to the use of cookies. more information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this. Please refer to our "privacy statement" and our "terms of use" for further information.