Back to article: Too much of a good thing: Overproduction of virulence factors impairs cryptococcal pathogenicity

FIGURE 2: Effective pathogenesis requires tight regulation of virulence factors. Optimum levels of capsule thickness and Titan cell formation are key to the success of wild-type infection (left); perturbation of this balance greatly reduces the pathogenicity of the pdr802 mutant strain (right).

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