Back to article: Cristae architecture is determined by an interplay of the MICOS complex and the F1FO ATP synthase via Mic27 and Mic10

FIGURE 6: Model for the functional interplay between the MICOS-complex and the F1FO-ATP synthase in yeast. Schematic representation of MICOS subunits in the mitochondrial inner membrane. Mic60 (pink) interacts (black arrow) via its C-terminus with protein complexes (grey) in the outer membrane (OM; e.g. the SAM-/TOB-complex). Mic27 (blue) mediates the interaction between Mic10 (green) and the remaining MICOS-complex. Mic10 interacts with part of the F1FO-ATP synthase (orange) via the dimer-specific F1FO-ATP synthase subunit e (Su e in pale green). Black lines indicate observed crosslinks. OM: outer membrane, IM: inner membrane.

By continuing to use the site, you agree to the use of cookies. more information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this. Please refer to our "privacy statement" and our "terms of use" for further information.