Back to article: The neuroprotective steroid progesterone promotes mitochondrial uncoupling, reduces cytosolic calcium and augments stress resistance in yeast cells

FIGURE 1: Progesterone treatment increases resistance of wildtype yeast to external stressors. ROS accumulation in yeast cells treated with progesterone (10 µg/ml) or left untreated as shown by the DHE to ethidium turnover rate upon hydrogen peroxide (A) or acetate (B) challenge during logarithmic phase. All data represent mean values (n = 3 ± SEM). Statistical analysis was conducted using non-paired Student’s t-test. * = p<0.05; ** = p<0.01; *** = p<0.001; n.s. = non-significant, Prog = progesterone, ctrl = control.

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