Back to article: Thiol trapping and metabolic redistribution of sulfur metabolites enable cells to overcome cysteine overload


FIGURE 2: Relative intracellular amounts of cysteine and cystine as a function of time in cells overexpressing either cysteine transporter and challenged with cysteine or cystine transporter and challenged with cystine.

(A) Relative levels of cysteine and cystine in S. cerevisiae cells expressing TEF-YCT1 treated with 500 µM cysteine measured at different time points.

(B) Relative levels of cysteine and cystine in S. cerevisiae cells expressing TEF-CgCYN1 treated with 500 µM cystine measured at different time points.