Back to article: Thiol trapping and metabolic redistribution of sulfur metabolites enable cells to overcome cysteine overload


FIGURE 7.

(A) Venn diagram showing a list of genes involved in specific pathways that are upregulated in S. cerevisiae cells expressing TEF-YCT1 treated with cysteine (500µM), TEF-CgCYN1 treated with cystine (500µM), where the genes commonly induced in both [p<0.05, fold change ≥ 2.0 (cysteine) and fold change ≥ 1.40 (cystine)] are emphasized.

(B) Venn diagram showing a list of genes involved in specific pathways that are down regulated in S. cerevisiae cells expressing TEF-YCT1 treated with cysteine (500µM), TEF-CgCYN1 treated with cystine (500µM) and set of genes common to both [p<0.05, fold change ≥ 1.5(cysteine) and fold change ≥ 0.8 (cystine)].