Publications

The mechanism of Tat-dependent protein translocation

May 15, 2026

This review integrates mechanistically relevant biochemical, molecular, and structural studies on Tat-dependent translocation of folded proteins into an in its molecular detail new comprehensive explanation of how the Tat system mediates protein transport.

Sugar-induced cell death (SICD) in Saccharomyces cerevisiae: insights into nitrogen-mediated rescue and apoptotic cell death pathways

May 11, 2026

This study examined mechanisms through which yeast sugar-induced cell death can be prevented. High concentrations of glucose induced a catastrophic response that was only rescued by highly preferred nitrogen sources and by preventing nuclear localization of specific cell death proteins.

From the gut to the lungs: The role of gut microbiota in chronic obstructive pulmonary disease and related research progress

April 15, 2026

This article provides new ideas and directions for the basic research and clinical practice of COPD by comprehensively sorting out the association between gut microbiota and COPD.

TOR-dependent regulation of the yeast homolog of the juvenile Batten Disease-associated gene CLN3

March 11, 2026

This study identifies conditions and genes that induce BTN1 expression in yeast. We show that BTN1 expression is regulated by translational control and by the mTOR1 pathway. An understanding of when and why BTN1 expression will aid in understanding the expression of CLN3, which may be helpful in the treatment of this devastating disease.

Metagenomic and microbiological analyses of historical manuscripts for bacterial community profiling and bacteria-related biodeterioration assessment

March 1, 2026

By documenting both culturable and non-culturable taxa, this work provides a foundational dataset for understanding bacterial contributions to manuscript stability and offers a methodological framework for future research on biodeterioration dynamics in Islamic and global documentary heritage.

Overcoming phagocytosis resistance of hypervirulent Klebsiella pneumoniae by directly targeting capsules

February 16, 2026

This study highlights a promising strategy for disarming hypervirulent K. pneumoniae by directly targeting its key virulence factors and provides novel insights into antibacterial therapeutic approaches against this clinically significant pathogen.

Protein arginine methyltransferases in protozoan parasites: a new path for antiparasitic chemotherapy?

February 12, 2026

This review discusses the activity and the relevance of arginine methyltransferases for the survival of pathogenic kinetoplastids, apicomplexans and amoebas, and how these enzymes could be exploited as drug targets.

VapA/Scs2 sustains polarized growth in Aspergillus nidulans by maintaining AP-2-mediated apical endocytosis

February 5, 2026

To explore the functional significance of ER–PM contact sites in filamentous fungi, we identified and genetically characterized all Aspergillus nidulans proteins homologous to Snc2/VAP, Ist2, or tricalbins.

Genetic make-up and regulation of the L-lysine biosynthesis pathway in Vibrio natriegens

February 3, 2026

This study analysed the make-up and regulation of the biosynthetic pathway for L-lysine and related L-aspartate family amino acids (AFAAs) in Vibrio natriegens DSM759 to provide a comprehensive basis for future metabolic engineering endeavours aiming at developing this strain into an amino acid overproducer.

Regulation of extracellular vesicles for protein secretion in Aspergillus nidulans

January 28, 2026

This study reveals that Aspergillus nidulans boosts extracellular vesicle production when ER-trafficked enzymes are induced, uncovering how fungi remodel their secretome through vesicle-mediated secretion to adapt to changing environments and biofilm formation.

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