Overexpression of the transcription factor Yap1 modifies intracellular redox conditions and enhances recombinant protein secretion

October 31, 2014

This article investigates the role of Yap1 during the production of recombinant secretory proteins in glucose based growth conditions in Pichia pastoris, and reports a novel role of Yap1 during ER-resident oxidative protein folding.