Direct detection of stringent alarmones (pp)pGpp using malachite green

August 5, 2024

In this study, we demonstrate the surprising discovery of a commercially available, low-cost malachite green (MG) detection kit, originally designed for orthophosphate (Pi) detection, for detecting (p)ppGpp and its analogues, especially pGpp

Evolution of the bacterial nucleosidase PpnN and its relation to the stringent response

July 16, 2019

This article comments on work published by Zhang et al (Mol Cell, 2019), which discovered an interesting mode of regulation of purine metabolism unique to Proteobacteria.