Yeast can express and assemble bacterial secretins in the mitochondrial outer membrane

November 19, 2019

Secretins, essential components of bacterial secretion systems, can be expressed in yeast and show differential dependencies on mitochondrial import and assembly factors for membrane integration, suggesting diverse pathways for their assembly into the bacterial outer membrane.

An extensive endoplasmic reticulum-localised glycoprotein family in trypanosomatids

October 1, 2014

This work describes a novel family of type I membrane proteins ("invariant glycoproteins") and proposes them as trypanosomatid-specific ER-localised glycoproteins, with potential contributions to life cycle progression and immunity, that utilise oligomerisation as an ER retention mechanism.