Transcriptomic response to different heme sources in Trypanosoma cruzi epimastigotes

January 23, 2026

This study uncovers how the Chagas disease parasite adapts to changes in heme, an essential molecule for its survival, providing transcriptional clues to heme metabolism and identifying a previously unreported heme-binding protein in T. cruzi.

Lipid and fatty acid metabolism in trypanosomatids

October 6, 2021

This work reviews specific aspects of lipid and fatty acid metabolism in the protozoan parasites T. brucei, T. cruzi, and Leishmania spp., as well as the pathways that have been explored for the development of new chemotherapies.