Back to article: Promoter methylation and increased expression of PD-L1 in patients with active tuberculosis


FIGURE 1: Comparisons of PD-L1, DNMTs, and TETs expression in peripheral blood mononuclear cells between (A) patients with active TB and non-TB subjects, and in (B) patients with active TB patients upon TB diagnosis and after anti-TB treatment. The data in bar charts are mean values of relative expression compared to GAPDH as reference. Differences between groups were compared using the Mann–Whitney U test. PD-L1 – programmed death-ligand 1; DNMTs – DNA methyltransferases; TETs – ten eleven translocation methylcytosine dioxygenases; 1M – 1-month after anti-TB treatment; 2M – 2-month after anti-TB treatment.

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