Back to article: A complex remodeling of cellular homeostasis distinguishes RSV/SARS-CoV-2 co-infected A549-hACE2 expressing cell lines


FIGURE 2: Assessment of in vitro RSV and SARS-CoV-2 viral replication. (A) SARS-CoV-2 and RSV viral replication was assessed by digital droplet PCR in single infection and co-infection conditions at 72 hpi. Significant differences between groups are indicated by * (Unpaired t test). Mean values ± SEM are reported. **p<0.01. (B) Representative immunofluorescence images acquired in 40X resolution of combined F-RSV and N-SARS-CoV-2 proteins 48 hpi in uninfected, SARS-CoV-2 single-infected, RSV single-infected and co-infected A549-hACE2 cells (DAPI in blue, phalloidin in red, N-SARS-CoV-2 in grey, F-RSV in green).

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