Featured article:
Nutritional and meiotic induction of transiently heritable stress resistant states in budding yeast
Heldder Gutierrez, Bakhtiyar Taghizada, and Marc D. Meneghini
Transient exposures to environmental stresses induce altered physiological states in exposed cells that persist after the stresses have been removed. These states, referred to as cellular memory, can even be passed on to daughter cells and may thus be thought of as embodying a form of epigenetic inheritance. We find that meiotically produced spores in the budding yeast S. cerevisiae possess a state of heightened stress resistance that, following their germination, persists for numerous mitotic generations. As yeast meiotic development is essentially a starvation response that a/alpha diploid cells engage, we sought to model this phenomenon by subjecting haploid cells to starvation conditions. We find also that haploid cells exposed to glucose withdrawal acquire a state of elevated stress resistance that persists after the reintroduction of these cells to glucose-replete media. Following release from lengthy durations of glucose starvation, we confirm that this (…)
About us
News
Meet the editorial board
Most viewed last month
- Formyl-methionine as a degradation signal at the N-termini of bacterial proteins
- Signaling pathways and posttranslational modifications of tau in Alzheimer’s disease: the humanization of yeast cells
- A chemical genetic screen reveals a role for proteostasis in capsule and biofilm formation by Cryptococcus neoformans
- Electron microscopy for ultrastructural analysis and protein localization in Saccharomyces cerevisiae
- Sulfur transfer and activation by ubiquitin-like modifier system Uba4•Urm1 link protein urmylation and tRNA thiolation in yeast
- Guidelines and recommendations on yeast cell death nomenclature
- Understanding structure, function, and mutations in the mitochondrial ATP synthase
- The MAPKKKs Ste11 and Bck1 jointly transduce the high oxidative stress signal through the cell wall integrity MAP kinase pathway
- Autophagy: machinery and regulation
- Live fast, die soon: cell cycle progression and lifespan in yeast cells
Publish with MIC
Connect with us
