Back to article: A genome-wide screen for FTY720-sensitive mutants reveals genes required for ROS homeostasis


FIGURE 2: FTY720-sensitivity screening using dilution-series spot assay for the 49 KO strains identified in third screen. (A) Raw data of chemical genomics screening on the YES plate with 0, 10, 20 μM FTY720 (YES, +F10, +F20) in the absence/presence of 5 mM NAC (+N). The genes shown in red affected the cytotoxicity of FTY720 and the reversibility by NAC (Group1). The genes shown in blue had growth defects in H2O2 sensitivity (Group2). (B) Venn diagram showing the result of A.

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