FIGURE 2: Extracellular Ca²⁺ availability affects intracellular Ca²⁺ dynamics in response to staurosporine.

(A) Aequorin-expressing wild type cells were cultured for 6 hours in the indicated media and after the addition of 20 μM staurosporine (STS), luminescence was followed over time. The STS-induced amplitude of response is shown.

(B) Quantification (in arbitrary units) of the cytosolic Ca²⁺ peaks “A” and “B” (indicated in A). *, p-value ≤ 0.05.