FIGURE 5: Deletion of SUM1 rescues defects in RLS and cellular health span of sir2∆ cells.

(A) RLSs of wild-type, sir2∆, sum1∆, and sir2∆sum1∆ cells were determined as described in Materials and Methods.

(B) Mean generation time was determined during the RLS assay as described in Materials and Methods. Error bars represent SEM. n = 40 cells per strain. Data is representative of 2 independent trials.