Back to article: Neutralizing the threat: harnessing broadly neutralizing antibodies against HIV-1 for treatment and prevention


FIGURE 1: Examples of potential forms of HIV-1 envelope on the viral surface. (A) Intact envelope spikes consist of three non-covalently bound gp120/gp41 heterodimers embedded in the viral membrane via a transmembrane domain and a cytoplasmic tail. (B) Free monomeric gp120, released through envelope shedding. (C) Shaved gp41 stumps on the viral surface.

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