FIGURE 3: Effect of Candesartan Cilexetil on Cu tolerance of yeast mutants.

Serial dilutions of wild type (WT), Δcta1, Δctt1, Δgrx5, Δsod1, Δsod2, Δyno1, Δcup2 and Δcrs5 were spotted onto control (0 mM Cu) or Cu-containing (1.25 mM – 1.5 mM) solid SC media in presence of control (0.5% DMSO; top panels) or 100 µM Candesartan Cilexetil (bottom panels). Growth was evaluated following 48 h incubation at 30°C. Data representative for two biological repeats.