FIGURE 3: Effect of DNA polymerase epsilon mutants and RNase H2 mutants on recombination rates.

(A) Recombination rates using the leu2 duplication reporter in strains with increased (pol2 M644G) or decreased (pol2 M644L) rNMP incorporation are shown. Median rates with 95% confidence limits (n = 18) are presented.

(B) Recombination rates using the ade2 duplication reporter in strains with increased (pol2 M644G) or decreased (pol2 M644L) rNMP incorporation are shown. Median rates with 95% confidence limits (n = 18) are presented.

(C) Recombination rates in an rnh201 P45D Y 219A strain are shown using the leu2 duplication reporter are shown. Median rates with 95% confidence limits (n = 18) are presented.

(D) Recombination rates in an rnh201 P45D Y 219A strain using the ade2 duplication reporter are shown. Median rates with 95% confidence limits (n = 18) are presented. The wild type (WT) and rnh201∆ rates are taken from panel B.

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