FIGURE 1: Efficiency of metabolic and transcriptional “futile cycles”.

Top panels illustrate repressive conditions for the generation of fructose 1,6-bisphosphate (resting muscle) and ATG8 transcripts (nutrient-replete conditions), respectively. Lower panels illustrate the corresponding inductive conditions, active muscle contraction and starvation, respectively. This figure was modified from figure 7 of Park et al., (2010) J. Biol. Chem. 285:34746.