FIGURE 1: Simplified phospholipid structure and the site of cleavage of Phospholipases A and Lysophospholipases. A phospholipid consists of a glycerol-3-phosphate esterified with nonpolar fatty acids at its sn-1 (R1) and sn-2 (R2) positions and a polar headgroup (X = choline, ethanolamine, serine…) at its phosphoryl group. Phospholipases A are named A1 or A2 depending on their site on cleavage and the resulting molecules, indicated by arrows. Lysophospholipases act on lysophospholipids previously hydrolyzed by a PLA [1].
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- Aloulou A, Rahier R, Arhab Y, Noiriel A, and Abousalham A (2018). Phospholipases: An Overview: Methods and Protocols. In: Methods in molecular biology (Clifton, N.J.). pp 69–105. 10.1007/978-1-4939-8672-9_3