Back to article: Gut microbial metabolites in depression: understanding the biochemical mechanisms


TABLE 9. Effects of microbial metabolites on depressive behavior in rodent and human studies.

AhR: Aryl Hydrocarbon Receptor; BBB: Blood Brain Barrier; BH4: Tetrahydrobiopterin; FXR: Farnesoid X Receptor; GPR41: G-protein cou-pled receptor 41; GPR43: G-protein coupled receptor 43; GPR81: G-protein coupled receptor 81; GTP: Guanosine triphosphate; HDACi: Histone deacetylase inhibitor; MDD: Major Depressive Disorder; NT: Neurotransmitter; PXR: Pregnane X receptor; SAM: S-adenosylmethionine; SCFA: Short-Chain Fatty Acids; TGR5: Takeda G-protein receptor 5; TMA: Trimethylamine; TMAO: Trimethylamine N-oxide; TUDCA: Tauroursodeoxycholic acids; VDR: Vitamin D Receptor.

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