FIGURE 1: Origin and composition of gram-positive EVs. (A) The release of EVs involves diversified events depending on the cell lytic enzyme viz. PGN degradation followed by cytoplasmic membrane bleb protrusion via endolysins and PGN remodelling via hydrolyzing enzyme autolysins. (B) The internal structure of EVs comprising of nucleic acids, virulence factors, and intracellular proteins.