Back to article: Broad-spectrum antifungal activities and mechanism of drimane sesquiterpenoids

FIGURE 3: Protection of Caenorhabditis elegans worms from C. albicans-mediated death by drimenol (1). C. albicans (yeast cells) fed larvae were incubated in RPMI medium without and with 1 (+Dri) (50 µg/ml) in a 96 well microtiter plate and incubated at 30°C for two to three days. Left panel without 1 shows dead worms (straight and immobile, arrows) due to C. albicans growth. Right panel shows a well containing 1 where worms were alive as judged by their movements and the lack of fungal growth.

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