Back to article: A multifunctional small RNA binding protein for sensing and signaling cell envelope precursor availability in bacteria

FIGURE 2: GlcN6P sensing and signaling by RapZ.(A) Regulatory cascade initiated by RapZ when sensing GlcN6P scarcity. (B) Cartoon representation of the X-ray crystal structure of tetrameric RapZ (upper panel). The middle panel shows localization of the RNA binding domain and a putative ligand binding pocket occupied by malonate within the RapZ-CTD swapped dimer. Bottom panel: Close-up view of the residues forming the presumptive GlcN6P binding site with bound sulfate. The cartoons illustrating the RapZ structure are from Gonzalez et al., 2017, Nucleic Acids Res. 45(18):10845-10860.

By continuing to use the site, you agree to the use of cookies. more information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this. Please refer to our "privacy statement" and our "terms of use" for further information.