Back to article: Cleavage-defective Topoisomerase I mutants sharply increase G-quadruplex-associated genomic instability
TABLE 2. Oligonucleotides used in binding assays. SµG oligo can adopt a G4 conformation while the M1 oligos cannot. Guanine-runs in SµG oligo are in bold. G>A mutations in M1 oligo introduced to disrupt guanine-runs are indicated as lowercase letters.
*G-score was calculated using QGRS Mapper (https://bioinformatics.ramapo.edu/QGRS/index.php; parameters: Max Length – 44, Min G-Group Size – 3, and Loop Size – 0 to 10).