Back to article: Cleavage-defective Topoisomerase I mutants sharply increase G-quadruplex-associated genomic instability

TABLE 2. Oligonucleotides used in binding assays. SµG oligo can adopt a G4 conformation while the M1 oligos cannot. Guanine-runs in SµG oligo are in bold. G>A mutations in M1 oligo introduced to disrupt guanine-runs are indicated as lowercase letters.

*G-score was calculated using QGRS Mapper (; parameters: Max Length – 44, Min G-Group Size – 3, and Loop Size – 0 to 10).

By continuing to use the site, you agree to the use of cookies. more information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this. Please refer to our "privacy statement" and our "terms of use" for further information.