Back to article: Multiple genome analysis of Candida glabrata clinical isolates renders new insights into genetic diversity and drug resistance determinants


FIGURE 3: Type distribution of genomic variants found exclusively in the genomes of resistant isolates. The assessed mutations are present in the genomes of azole resistant (A), echinocandin intermediate (B), echinocandin resistant (C) and multi resistant (D) isolates, being absent from the genomes of susceptible isolates. For each resistance group, the catalogued mutations are specific to that group. Variant type was predicted with SnpEff [10].

10. Cingolani P, Platts A, Wang LL, Coon M, Nguyen T, Wang L, Land SJ, Lu X, and Ruden DM (2012). A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3. Fly 6(2): 80. 10.4161/FLY.19695

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