FIGURE 1: Comparative analysis of physiological parameters of the parental and hrk1Δ strains under acetic acid-stressed and non-stressed cultivations. Growth curves (A), plasma membrane H⁺-ATPase activity (B), and intracellular pH (pHi) (C) of S. cerevisiae BY4741 (parental strain ●/○) and the hrk1Δ deletion mutant strain (■/□) cultivated in YNB/YNB^pH medium (●/■) or in YNB/YNB^pH supplemented with 50 mM acetic acid (○/□) at pH 4.0. The displayed results for ATPase activity measurements are derived from an experiment representative of other independent experiments leading to similar results. In the case of pHi, the data presented represents average values ± SD of at least two independent experiments.