Back to article: Fecal gelatinase does not predict mortality in patients with alcohol-associated hepatitis


FIGURE 2: Fecal gelatinase is not an important feature for 30-day or 90-day survival in patients with alcohol-associated hepatitis per random forest analysis. (A) Mean decrease Gini score and (B) mean decrease accuracy for 30-day mortality by random forest analysis were quantitated for presence of gelatinase and multiple liver disease markers to determine their respective feature importance for mortality. (C) Mean decrease Gini score and (D) mean decrease accuracy for 90-day mortality by random forest analysis were quantitated for gelatinase and multiple liver disease markers to determine their respective feature importance for mortality (Gelatinase n=60, Child-Pugh n=57, FIB-4 n=57, Maddrey’s DF n=52, ABIC n=59, MELD score n=59, and MELD- Na score n=59). ABIC, ‘Age, serum bilirubin, INR, and serum creatinine score’; FIB-4, Fibrosis-4 Index; INR, international normalized ratio; Maddrey’s DF, Maddrey’s Discriminant Function; MELD, model for end-stage liver disease; MELD-Na, sodium-adjusted model for end-stage liver disease.

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