Back to article: A chemical genetic screen reveals a role for proteostasis in capsule and biofilm formation by Cryptococcus neoformans

FIGURE 2: Phosphoglucomutase does not appear to be a major target of lithium in C. neoformans. Growth curve analysis for C. neoformans H99S in YNB medium containing either 2% glucose or 2% galactose as sole carbon source at 30°C in the absence (control) or presence of lithium chloride (LiCl). Solid lines represent the means of results from two independent experiments, each performed in quadruplicate, and shaded areas represent the standard errors of the means. (B) Relative growth data from panel A. Results were plotted relative to the untreated controls. Note that cells grown in galactose were less sensitive to elevated LiCl concentrations compared to cells grown in glucose. Glu, glucose; Gal, galactose.

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