Back to article: Impact of histone H4K16 acetylation on the meiotic recombination checkpoint in Saccharomyces cerevisiae

FIGURE 2: The meiotic recombination checkpoint is impaired in H4-K16R and H4-K16Q mutants.

(A) Dityrosine fluorescence, as an indicator of sporulation, was examined after 3 days of sporulation on plates.

(B) Time course of meiotic nuclear divisions; the percentage of cells containing two or more nuclei is represented.

(C) Spore viability, as assessed by asci dissection, is presented. At least 144 spores were scored for each strain. Strains used in (A) are DP421 (wild type), DP994 (H4-K16R), DP1000 (H4-K16Q), DP422 (zip1), DP995 (zip1 H4-K16R) and DP1001 (zip1 H4-K16Q). Strains used in (B) and (C) are DP634 (wild type), DP635 (H4-K16R), DP636 (H4-K16Q), DP639 (zip1), DP640 (zip1 H4-K16R) and DP641 (zip1 H4-K16Q).

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