Back to article: The tug-of-war over MTOR in Legionella infections

FIGURE 1: MTOR role in Legionella macrophage infections.

(A) A representative micrograph depicting robust MTOR signaling in an infected Myd88-/- BMM (*) but not in an adjacent bystander cell.

(B) The balance between multiple regulatory mechanisms dictates MTOR signaling in the Legionella infected macrophages.

(C) Putative LCV expansion mechanisms through (i) fusion with membrane-bound organelles, (ii) de novo lipogenesis at the LCV or (iii) through ER-derived membrane infusion.

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