Translate to divide: сontrol of the cell cycle by protein synthesis

Authors:

Michael Polymenis1 and Rodolfo Aramayo2
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Affiliations:

1 Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA.

2 Department of Biology, Texas A&M University, College Station, TX 77843, USA.

Keywords: 

protein synthesis, ribosome biogenesis, ribosome profiling, START, translational control

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Corresponding Author(s):

Michael Polymenis, Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA polymenis@tamu.edu Rodolfo Aramayo, Department of Biology, Texas A&M University, College Station, TX 77843, USA raramayo@tamu.edu

Conflict of interest statement:

The authors declare no conflict of interest.

Please cite this article as:

Michael Polymenis and Rodolfo Aramayo (2015). Translate to divide: Control of the cell cycle by protein synthesis. Microbial Cell 2(4): 94-104.

© 2015 Polymenis and Aramayo. This is an open-access article released under the terms of the Creative Commons Attribution (CC BY) license, which allows the unrestricted use, distribution, and reproduction in any medium, provided the original author and source are acknowledged.

Abstract:

Protein synthesis underpins much of cell growth and, consequently, cell multiplication. Understanding how proliferating cells commit and progress into the cell cycle requires knowing not only which proteins need to be synthesized, but also what determines their rate of synthesis during cell division.

doi: 10.15698/mic2015.04.198
Volume 2, pp. 94 to 104, published 20/03/2015.