Vol. 13, 2026
The transcriptome of dendritic cells redraws the boundaries between pathogenicity and commensalism in yeast
Lisa Rizzetto1, Irene Stefanini2, Stefano Nenciarini3, Monica Di Paola3, Samantha Riccadonna1, Ivo G. Gut4,5, Marta Gut4,5, Simon Heath4,5 and Duccio Cavalieri3
Our immune system meets many fungi, but reacts strongly to only a few. The comparison of key fungal species showed that responses differ mainly in timing and not just genes, highlighting the need to rethink what makes fungi harmful vs. harmless.
Yippee-like protein Moh1 links gene expression to metabolism and selective stress resistance in Saccharomyces cerevisiae
Çağla Ece Olgun1,a, Gizem Turan Duman1,a, Gizem Güpür1, Hamit İzgi1, Mariam Huda2, Demet Çetin3, Zekiye Suludere4, Fatma Küçük Baloğlu5, Ayşe Koca Çaydaşı2 and Mesut Muyan1
This study demonstrates that the conserved yeast protein Moh1 links metabolism, gene expression, and cell structure, thereby altering cell envelope permeability and leading to selective stress responses.
Fungistatic effect of sorbic acid on yeast cells via translational repression involving eIF2α phosphorylation and formation of Ded1- and eIF2B-granules
Haruka Yoshiyama1, Wataru Nomura2 and Shingo Izawa1
The findings of this study provide new insights into the physiological effects of sorbic acid on yeast cells, specifically regarding the regulation of translation-related factors.
Occlusal types shape oral microbiome stomatotypes and metabolic landscapes: A multi-omics perspective on host-microbe interaction
Yufeng Duan1,a, Zheng Liu2,3,a, Wenting Lu1,a, Ning Zhao1, Lingjun Yuan1, Zhenxia Li1, Ting Zhou1, Shengzhao Xiao1, Dian Jing1, Xiaowen Zheng1, Wentao Shi4, Chao Liu1,*, Haixia Lu5,*, Qiang Feng6,* and Bing Fang1,*
This study reveals how occlusal types shape oral microbiome “stomatotypes” and metabolic profiles in adolescents. It offers fresh insights that host anatomy drives microecology which may be associated with personalized oral health.
Prohibitins: emerging host targets of bacteria and viruses at the plasma membrane, mitochondria, and cytoplasm
Grecia O. Rivera-Palomino1,2 and Arianne L. Theiss1,2,3
Prohibitins are emerging as central host hubs exploited by bacteria and viruses to rewire signaling and mitochondrial dynamics. The current review discusses Prohibitins in host-pathogen interplay and their potential as novel anti-infective targets.
Outer membrane vesicles in Vibrio species: Roles in biofilm formation and pathogenesis
Kumari Shambhavi and Durg Vijai Singh
This review explores current knowledge on outer membrane vesicles (OMVs) in Vibrio species, highlighting their roles in pathogenesis, host interaction, and marine ecology; and identifies major knowledge gaps, outlining key methodological challenges and future prospects for OMV-based applications.
Genomic epidemiology of carbapenemase-producing Klebsiella pneumoniae circulating in a Chilean tertiary-care hospital (2021–2022): Molecular characterization, resistance-virulence convergence, and clinical associations
Gustavo Araya1,2, Alhejandra Álvarez1, Carolina Arellano1, Rodrigo Bravo3, Abraham Gajardo4,5, Boris Barrera6, Francisco Silva6 and Roberto M. Vidal1
This study characterized carbapenem-resistant Kp (CR-Kp) strains isolated at the Hospital Clínico Universidad de Chile (HCUCH) 2021-2022 and explored associations with clinical characteristics.
The mechanism of Tat-dependent protein translocation
Thomas Brüser1,* and Carsten Sanders2,3,4
This review integrates mechanistically relevant biochemical, molecular, and structural studies on Tat-dependent translocation of folded proteins into an in its molecular detail new comprehensive explanation of how the Tat system mediates protein transport.
Sugar-induced cell death (SICD) in Saccharomyces cerevisiae: insights into nitrogen-mediated rescue and apoptotic cell death pathways
Raveena Parbhudayal and Hai-Ping Cheng
This study examined mechanisms through which yeast sugar-induced cell death can be prevented. High concentrations of glucose induced a catastrophic response that was only rescued by highly preferred nitrogen sources and by preventing nuclear localization of specific cell death proteins.
The transcriptome of dendritic cells redraws the boundaries between pathogenicity and commensalism in yeast
Lisa Rizzetto1, Irene Stefanini2, Stefano Nenciarini3, Monica Di Paola3, Samantha Riccadonna1, Ivo G. Gut4,5, Marta Gut4,5, Simon Heath4,5 and Duccio Cavalieri3
Our immune system meets many fungi, but reacts strongly to only a few. The comparison of key fungal species showed that responses differ mainly in timing and not just genes, highlighting the need to rethink what makes fungi harmful vs. harmless.
Yippee-like protein Moh1 links gene expression to metabolism and selective stress resistance in Saccharomyces cerevisiae
Çağla Ece Olgun1,a, Gizem Turan Duman1,a, Gizem Güpür1, Hamit İzgi1, Mariam Huda2, Demet Çetin3, Zekiye Suludere4, Fatma Küçük Baloğlu5, Ayşe Koca Çaydaşı2 and Mesut Muyan1
This study demonstrates that the conserved yeast protein Moh1 links metabolism, gene expression, and cell structure, thereby altering cell envelope permeability and leading to selective stress responses.
Fungistatic effect of sorbic acid on yeast cells via translational repression involving eIF2α phosphorylation and formation of Ded1- and eIF2B-granules
Haruka Yoshiyama1, Wataru Nomura2 and Shingo Izawa1
The findings of this study provide new insights into the physiological effects of sorbic acid on yeast cells, specifically regarding the regulation of translation-related factors.
Occlusal types shape oral microbiome stomatotypes and metabolic landscapes: A multi-omics perspective on host-microbe interaction
Yufeng Duan1,a, Zheng Liu2,3,a, Wenting Lu1,a, Ning Zhao1, Lingjun Yuan1, Zhenxia Li1, Ting Zhou1, Shengzhao Xiao1, Dian Jing1, Xiaowen Zheng1, Wentao Shi4, Chao Liu1,*, Haixia Lu5,*, Qiang Feng6,* and Bing Fang1,*
This study reveals how occlusal types shape oral microbiome “stomatotypes” and metabolic profiles in adolescents. It offers fresh insights that host anatomy drives microecology which may be associated with personalized oral health.
Prohibitins: emerging host targets of bacteria and viruses at the plasma membrane, mitochondria, and cytoplasm
Grecia O. Rivera-Palomino1,2 and Arianne L. Theiss1,2,3
Prohibitins are emerging as central host hubs exploited by bacteria and viruses to rewire signaling and mitochondrial dynamics. The current review discusses Prohibitins in host-pathogen interplay and their potential as novel anti-infective targets.
Outer membrane vesicles in Vibrio species: Roles in biofilm formation and pathogenesis
Kumari Shambhavi and Durg Vijai Singh
This review explores current knowledge on outer membrane vesicles (OMVs) in Vibrio species, highlighting their roles in pathogenesis, host interaction, and marine ecology; and identifies major knowledge gaps, outlining key methodological challenges and future prospects for OMV-based applications.
Prohibitins: emerging host targets of bacteria and viruses at the plasma membrane, mitochondria, and cytoplasm
Grecia O. Rivera-Palomino1,2 and Arianne L. Theiss1,2,3
Prohibitins are emerging as central host hubs exploited by bacteria and viruses to rewire signaling and mitochondrial dynamics. The current review discusses Prohibitins in host-pathogen interplay and their potential as novel anti-infective targets.
Outer membrane vesicles in Vibrio species: Roles in biofilm formation and pathogenesis
Kumari Shambhavi and Durg Vijai Singh
This review explores current knowledge on outer membrane vesicles (OMVs) in Vibrio species, highlighting their roles in pathogenesis, host interaction, and marine ecology; and identifies major knowledge gaps, outlining key methodological challenges and future prospects for OMV-based applications.
The mechanism of Tat-dependent protein translocation
Thomas Brüser1,* and Carsten Sanders2,3,4
This review integrates mechanistically relevant biochemical, molecular, and structural studies on Tat-dependent translocation of folded proteins into an in its molecular detail new comprehensive explanation of how the Tat system mediates protein transport.
From the gut to the lungs: The role of gut microbiota in chronic obstructive pulmonary disease and related research progress
Simin Yang1,2, Shuting Zeng1,2, Yongan Deng1,2, Xiaodong Duan1,2, Chengkai Chen1,2, Luyun Sun2, Yongkang Qiao2 and Zunpeng Shu1,2
This article provides new ideas and directions for the basic research and clinical practice of COPD by comprehensively sorting out the association between gut microbiota and COPD.
Protein arginine methyltransferases in protozoan parasites: a new path for antiparasitic chemotherapy?
Gustavo D. Campagnaro1,* and Sébastien Pomel2
This review discusses the activity and the relevance of arginine methyltransferases for the survival of pathogenic kinetoplastids, apicomplexans and amoebas, and how these enzymes could be exploited as drug targets.
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The transcriptome of dendritic cells redraws the boundaries between pathogenicity and commensalism in yeast
July 7, 2026
Our immune system meets many fungi, but reacts strongly to only a few. The comparison of key fungal species showed that responses differ mainly in timing and not just genes, highlighting the need to rethink what makes fungi harmful vs. harmless.
Yippee-like protein Moh1 links gene expression to metabolism and selective stress resistance in Saccharomyces cerevisiae
June 29, 2026
This study demonstrates that the conserved yeast protein Moh1 links metabolism, gene expression, and cell structure, thereby altering cell envelope permeability and leading to selective stress responses.
Fungistatic effect of sorbic acid on yeast cells via translational repression involving eIF2α phosphorylation and formation of Ded1- and eIF2B-granules
June 17, 2026
The findings of this study provide new insights into the physiological effects of sorbic acid on yeast cells, specifically regarding the regulation of translation-related factors.
Prohibitins: emerging host targets of bacteria and viruses at the plasma membrane, mitochondria, and cytoplasm
June 3, 2026
Prohibitins are emerging as central host hubs exploited by bacteria and viruses to rewire signaling and mitochondrial dynamics. The current review discusses Prohibitins in host-pathogen interplay and their potential as novel anti-infective targets.
Outer membrane vesicles in Vibrio species: Roles in biofilm formation and pathogenesis
June 2, 2026
This review explores current knowledge on outer membrane vesicles (OMVs) in Vibrio species, highlighting their roles in pathogenesis, host interaction, and marine ecology; and identifies major knowledge gaps, outlining key methodological challenges and future prospects for OMV-based applications.
Genomic epidemiology of carbapenemase-producing Klebsiella pneumoniae circulating in a Chilean tertiary-care hospital (2021–2022): Molecular characterization, resistance-virulence convergence, and clinical associations
May 21, 2026
This study characterized carbapenem-resistant Kp (CR-Kp) strains isolated at the Hospital Clínico Universidad de Chile (HCUCH) 2021-2022 and explored associations with clinical characteristics.
The mechanism of Tat-dependent protein translocation
May 15, 2026
This review integrates mechanistically relevant biochemical, molecular, and structural studies on Tat-dependent translocation of folded proteins into an in its molecular detail new comprehensive explanation of how the Tat system mediates protein transport.