Cristae architecture is determined by an interplay of the MICOS complex and the F₁F_O ATP synthase via Mic27 and Mic10

July 20, 2017

This article investigates the roles of MICOS subunits Mic27 and Mic10, revealing their antagonistic and cooperative interactions in crista junction formation and cristae membrane curvature, and proposes a model where F1FO-ATP synthase is connected to MICOS, influencing CJ formation.