Unresolved mystery of cyclic nucleotide second messengers, periplasmic acid phosphatases and bacterial natural competence

July 18, 2024

In this study we aimed to identify the promotors responsible for the expression of the non-specific acid phosphatase AphA during different starvation conditions, to confirm the requirement of the cAMP-dependent CRP regulon for aphA expression, and to finally identify regulators of its expression.

Bacterial outer membrane vesicle biogenesis: a new mechanism and its implications

May 10, 2016

This article comments on work published by Roier et al. (Nat Commun, 2016), which proposes a novel and highly conserved bacterial outer membane vesicle biogenesis mechanism based on phospholipid accumulation in the outer leaflet of the outer membrane.