FIGURE 2: The implication of the Arabidopsis BAG-family proteins in various cellular processes linked to abiotic and biotic stress responses, and cell death regulation. The function of the nuclear BAG1-3, and mitochondrial localized BAG5 is currently unknown. BAG4 was shown to bind Hsp/Hsc 70 molecular chaperones, and is involved in cell death inhibition in response to abiotic stress. BAG6 is proteolytically activated, and functions as an adaptor protein linking fungal/chitin perception to the induction of autophagy. The ER localized BAG7, binds the molecular chaperone BiP2, and is an essential component of the unfolded protein response (UPR).

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