FIGURE 3: Pho85 involvement in cell cycle progression.

The cyclin Cln3 is phosphorylated by Pho85-Pho80 as a response to phosphate presence, resulting in increased stability of the cyclin and permitting it to reach the threshold for cell cycle progression through G1. Pho85-Clg1 can also phosphorylate Cln3, although at different residues, promoting its degradation as a response to nitrogen scarcity.

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