FIGURE 6: Invasion of ex vivo colonic explants was impaired for CSP-AS trophozoites.

Histological examination of colonic tissue sections after 7 h of infection with E. histolytica WT, GFP, CSP-AS strains and in the absence of trophozoites (control). Tissue cross-sections were stained with hematoxylin/eosin reagent. Trophozoites were revealed with an antibody against Gal/GalNAc lectin and appear in red. WT and GFP trophozoites were able to invade the mucosa. In contrast, trophozoites expressing the CSP-AS construct were unable to invade the lamina propria and tended to remain at the surface of the mucosa. Images are representative of three individual experiments. Scale bar: 10 µm.

By continuing to use the site, you agree to the use of cookies. more information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this. Please refer to our "privacy statement" and our "terms of use" for further information.