A novel BR-SMAD is required for larval development in barber’s pole worm Haemonchus contortus

Affiliations:

¹ State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, People’s Republic of China.

² Department of Molecular Parasitology, Faculty of Life Sciences, Humboldt University, Berlin, Germany.

³ Department of Biological Sciences, Birla Institute of Technology and Science Pilani (BITS-P), Hyderabad, India.

Keywords: 

Haemonchus contortus, R-SMADs, BMP subfamily, RNAi, larval development.

Abbreviations:

AR-SMAD – activin/TGF-β/nodal activated R-SMAD,

BMP – bone morphogenic protein,

BR-SMAD – BMP and differentiation factor/Müllerian inhibiting substance activated R-SMAD,

Co-SMAD – common-mediator SMAD,

DBL1 – Dpp and BMP-like-1,

dsRNA – double strand RNA,

MH – mad homology domain,

NLS – nuclear localization sequence,

R-SMAD – receptor-regulated SMAD,

siRNA – small interfering RNA,

TGF-β – transforming growth factor β.

Corresponding Author(s):

Conflict of interest statement:

The authors declare no conflict of interest.

Please cite this article as:

Fangfang Li, Peixi Qin, Lisha Ye, Nishith Gupta and Min Hu (2020). A novel BR-SMAD is required for larval develop-ment in barber’s pole worm, Haemonchus contortus. Microbial Cell 8(2): 57-64. doi: 10.15698/mic2021.02.742

© 2020 Li et al. This is an open-access article released under the terms of the Creative Commons Attribution (CC BY) license, which allows the unrestricted use, distribution, and reproduction in any medium, provided the original author and source are acknowledged.