Affiliations: Department of Biochemistry and Biophysics, Texas A&M University, 300 Olsen Blvd. College Station, TX, 77843, U.S.A.
Keywords:
metabolic labeling, exponential, linear, single-cell fluorescence.
Corresponding Author(s):
Conflict of interest statement:
The authors have no conflicts to declare.
Please cite this article as:
Eun-Gyu No, Heidi M Blank, Michael Polymenis (2024). Patterns of protein synthesis in the budding yeast cell cycle: variable or constant?. Microbial Cell 11: 321-327. doi: 10.15698/mic2024.08.835
© 2024 No et al. This is an open-access article released under the terms of the Creative Commons Attribution (CC BY) license, which allows the unrestricted use, distribution, and reproduction in any medium, provided the original author and source are acknowledged.
Patterns of protein synthesis in the budding yeast cell cycle: variable or constant?
Authors:Eun-Gyu No, Heidi M Blank and Michael Polymenis
doi: 10.15698/mic2024.08.835
Volume 11, pp. 321 to 327, published 20/08/2024.
Department of Biochemistry and Biophysics, Texas A&M University, 300 Olsen Blvd. College Station, TX, 77843, U.S.A.
Keywords:
metabolic labeling, exponential, linear, single-cell fluorescence.
Corresponding Author(s):
Conflict of interest statement:
The authors have no conflicts to declare.
Please cite this article as:
Eun-Gyu No, Heidi M Blank, Michael Polymenis (2024). Patterns of protein synthesis in the budding yeast cell cycle: variable or constant?. Microbial Cell 11: 321-327. doi: 10.15698/mic2024.08.835
© 2024 No et al. This is an open-access article released under the terms of the Creative Commons Attribution (CC BY) license, which allows the unrestricted use, distribution, and reproduction in any medium, provided the original author and source are acknowledged.
Abstract:
Proteins are the principal macromolecular constituent of proliferating cells, and protein synthesis is viewed as a primary metric of cell growth. While there are celebrated examples of proteins whose levels are periodic in the cell cycle (e.g., cyclins), the concentration of most proteins was not thought to change in the cell cycle, but some recent results challenge this notion. The ‘bulk’ protein is the focus of this article, specifically the rate of its synthesis, in the budding yeast Saccharomyces cerevisiae.